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Dr. Johanna W. Lampe

Fred Hutchinson Cancer Research Center
Public Health Sciences Division
Cancer Prevention Program
Full Member     Appointed: 2004

University of Washington
School of Public Health and Community Medicine
Epidemiology
Research Professor     Appointed: 2006
Johanna W. Lampe
Mailing Address
Fred Hutchinson Cancer Research Center
1100 Fairview Ave. N., M4-B402
P.O. Box 19024
Seattle, Washington 98109
United States
Contact Information
jlampe@fhcrc.org
Qualifications
B.S., University of Minnesota, Nutrition and Dietetics, 1982
R.D., University of Minnesota, Nutrition and Dietetics, 1982
Ph.D., University of Minnesota, Nutrition Sciences, 1990
Expertise and Research Interests
My research interests relate to understanding the mechanisms by which components of diet, particularly constituents of plant foods, alter risk factors for cancer. We use controlled dietary studies and other types of interventions in humans to examine biologic responses to diet and to evaluate biomarkers of dietary exposure. Several of our recent studies have focused on gene-diet interactions in relation to biotransformation enzyme activities. Numerous low-penetrance, high-prevalence genetic polymorphisms in metabolizing enzymes, such as the cytochromes P450 and conjugating enzymes (e.g., glutathione S-transferases, UDP-glucuronosyltransferases), can contribute to interindividual variation in enzyme activities. Many of these enzymes metabolize and inactivate potential carcinogens and cancer-promoting agents. They can also metabolize various compounds in plant foods and can be induced by specific phytochemicals. The relationship between genetic differences in enzyme activities and differences in plant food intake may be an important determinant of cancer susceptibility. Controlled feeding studies in humans are a useful method to examine these interactions.

The Lampe laboratory also investigates the metabolism and activities of isoflavones and lignans (estrogenic compounds found in soybeans and other plant foods). The phytoestrogens, like other plant food constituents, are made more biologically active when they undergo bacterial metabolism in the colon. Differences in colonic bacterial populations and aspects of diet that alter colonic environment influence exposure to potential chemoprotective agents. We are using cross-sectional, intervention, and in vitro studies to determine how dietary factors contribute to these differences in metabolism, whether metabolism can be altered by diet, and what are the biologic implications of these metabolic differences, particularly in relation to colorectal neoplasia. The laboratory also measures phytoestrogen concentrations in biologic samples for several large-scale epidemiologic studies.
Keywords
COS Keywords: Cancer or Carcinogenesis; Cancer Prevention; Epidemiology; Nutrition or Dietetics; Phytochemistry
Additional Terms: Biotransformation Enzymes; Diet; Lignans; Phytochemical
Memberships
American Association for Cancer Research
American Dietetic Association
American Society for Nutritional Sciences
Society for Experimental Biology and Medicine
Previous Positions
2002-2006, Research Associate Professor, University of Washington
1999-2004, Associate Member, Fred Hutchinson Cancer Research Center
1999-2002, Research Assistant Professor, University of Washington
1998-1999, Assistant Member, Fred Hutchinson Cancer Research Center
1994-1998, Associate, Fred Hutchinson Cancer Research Center
1993-1994, Research Associate, University of Minnesota, Food, Agricultural & Natural Resource Sciences, College of-Minneapolis/St. Paul, Food Science & Nutrition
Publications
  • Saracino MR, Bigler J, Schwarz Y, Chang JL, Li S, Li L, White E, Potter JD, Lampe JW (Mar 2009) Citrus fruit intake is associated with lower serum bilirubin concentration among women with the UGT1A1*28 polymorphism., The Journal of Nutrition, 139(3)555-60 Abstract

  • Yong M, Atkinson C, Newton KM, Aiello Bowles EJ, Stanczyk FZ, Westerlind KC, Holt VL, Schwartz SM, Leisenring WM, Lampe JW (Mar 2009) Associations between endogenous sex hormone levels and mammographic and bone densities in premenopausal women., Cancer Causes & Control : CCC Abstract

  • Lampe JW (Mar 2009) Interindividual differences in response to plant-based diets: implications for cancer risk., The American Journal of Clinical Nutrition Abstract

  • Hooper L, Ryder JJ, Kurzer MS, Lampe JW, Messina MJ, Phipps WR, Cassidy A (Mar 2009) Effects of soy protein and isoflavones on circulating hormone concentrations in pre- and post-menopausal women: a systematic review and meta-analysis., Human Reproduction Update Abstract

  • Gonzalez A, Peters U, Lampe JW, White E (2009) Zinc intake from supplements and diet and prostate cancer., Nutrition and Cancer, 61(2)206-15 Abstract

  • Atkinson C, Newton KM, Stanczyk FZ, Westerlind KC, Li L, Lampe JW (Dec 2008) Daidzein-metabolizing phenotypes in relation to serum hormones and sex hormone binding globulin, and urinary estrogen metabolites in premenopausal women in the United States., Cancer causes & control : CCC, 19(10)1085-93 Abstract

  • Guyman LA, Adlercreutz H, Koskela A, Li L, Beresford SA, Lampe JW (Oct 2008) Urinary 3-(3,5-dihydroxyphenyl)-1-propanoic acid, an alkylresorcinol metabolite, is a potential biomarker of whole-grain intake in a U.S. population., The Journal of nutrition, 138(10)1957-62 Abstract

  • Lampe JW (Oct 2008) The Human Microbiome Project: getting to the guts of the matter in cancer epidemiology., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 17(10)2523-4 Abstract

  • Atkinson C, Newton KM, Aiello Bowles EJ, Lehman CD, Stanczyk FZ, Westerlind KC, Li L, Lampe JW (Sep 2008) Daidzein-metabolizing phenotypes in relation to mammographic breast density among premenopausal women in the United States., Breast cancer research and treatment Abstract

  • Maruti SS, Chang JL, Prunty JA, Bigler J, Schwarz Y, Li SS, Li L, King IB, Potter JD, Lampe JW (Jul 2008) Serum beta-glucuronidase activity in response to fruit and vegetable supplementation: a controlled feeding study., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 17(7)1808-12 Abstract

  • Atkinson C, Newton KM, Bowles EJ, Yong M, Lampe JW (Mar 2008) Demographic, anthropometric, and lifestyle factors and dietary intakes in relation to daidzein-metabolizing phenotypes among premenopausal women in the United States., The American journal of clinical nutrition, 87(3)679-87 Abstract

  • Chia VM, Newcomb PA, White E, Zheng Y, Potter JD, Lampe JW (2008) Reproducibility of serum leptin, insulin-like growth factor-I, and insulin-like growth factor-binding protein-3 measurements., Hormone research, 69(5)295-300 Abstract

  • Gonzalez A, Peters U, Lampe JW, Satia JA, White E (Jan 2008) Correlates of toenail zinc in a free-living U.S. population., Annals of epidemiology, 18(1)74-7 Abstract

  • Gonzalez A, Peters U, Lampe JW, White E (Dec 2007) Boron intake and prostate cancer risk., Cancer causes & control : CCC, 18(10)1131-40 Abstract

  • Lampe JW, Nishino Y, Ray RM, Wu C, Li W, Lin MG, Gao DL, Hu Y, Shannon J, Stalsberg H, Porter PL, Frankenfeld CL, Wähälä K, Thomas DB (Dec 2007) Plasma isoflavones and fibrocystic breast conditions and breast cancer among women in Shanghai, China., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 16(12)2579-86 Abstract

  • Lampe JW, Nishino Y, Ray RM, Wu C, Li W, Lin MG, Gao DL, Hu Y, Shannon J, Stalsberg H, Porter PL, Frankenfeld CL, Wähälä K, Thomas DB (Dec 2007) Plasma isoflavones and fibrocystic breast conditions and breast cancer among women in Shanghai, China., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 16(12)2579-86 Abstract

  • Chia VM, Newcomb PA, Lampe JW, White E, Mandelson MT, McTiernan A, Potter JD (Dec 2007) Leptin concentrations, leptin receptor polymorphisms, and colorectal adenoma risk., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 16(12)2697-703 Abstract

  • Abrahamson PE, King IB, Ulrich CM, Rudolph RE, Irwin ML, Yasui Y, Surawicz C, Lampe JW, Lampe PD, Morgan A, Sorensen BE, Ayub K, Potter JD, McTiernan A (Nov 2007) No effect of exercise on colon mucosal prostaglandin concentrations: a 12-month randomized controlled trial., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 16(11)2351-6 Abstract

  • Siahpush SH, Vaughan TL, Lampe JN, Freeman R, Lewis S, Odze RD, Blount PL, Ayub K, Rabinovitch PS, Reid BJ, Chen C (Nov 2007) Longitudinal study of insulin-like growth factor, insulin-like growth factor binding protein-3, and their polymorphisms: risk of neoplastic progression in Barrett's esophagus., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 16(11)2387-95 Abstract

  • Lampe JW, Chang JL (Oct 2007) Interindividual differences in phytochemical metabolism and disposition., Seminars in cancer biology, 17(5)347-53 Abstract

  • Campbell KL, McTiernan A, Li SS, Sorensen BE, Yasui Y, Lampe JW, King IB, Ulrich CM, Rudolph RE, Irwin ML, Surawicz C, Ayub K, Potter JD, Lampe PD (Sep 2007) Effect of a 12-month exercise intervention on the apoptotic regulating proteins Bax and Bcl-2 in colon crypts: a randomized controlled trial., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 16(9)1767-74 Abstract

  • Chen Y, Kuehl GE, Bigler J, Rimorin CF, Schwarz Y, Shen DD, Lampe JW (Aug 2007) UGT1A6 polymorphism and salicylic acid glucuronidation following aspirin., Pharmacogenetics and genomics, 17(8)571-9 Abstract

  • Greenlee H, Atkinson C, Stanczyk FZ, Lampe JW (Aug 2007) A pilot and feasibility study on the effects of naturopathic botanical and dietary interventions on sex steroid hormone metabolism in premenopausal women., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 16(8)1601-9 Abstract

  • McTiernan A, Sorensen B, Irwin ML, Morgan A, Yasui Y, Rudolph RE, Surawicz C, Lampe JW, Lampe PD, Ayub K, Potter JD (Jun 2007) Exercise effect on weight and body fat in men and women., Obesity (Silver Spring, Md.), 15(6)1496-512 Abstract

  • Chang JL, Bigler J, Schwarz Y, Li SS, Li L, King IB, Potter JD, Lampe JW (Apr 2007) UGT1A1 polymorphism is associated with serum bilirubin concentrations in a randomized, controlled, fruit and vegetable feeding trial., The Journal of nutrition, 137(4)890-7 Abstract

  • Shannon J, King IB, Moshofsky R, Lampe JW, Gao DL, Ray RM, Thomas DB (Apr 2007) Erythrocyte fatty acids and breast cancer risk: a case-control study in Shanghai, China., The American journal of clinical nutrition, 85(4)1090-7 Abstract

  • Anderson CA, Beresford SA, Lampe J, Knopp RH, Motulsky AG (2007) Enhancing recruitment of healthy African American volunteers in a city with a small African American community: results from a dietary supplement crossover trial., Ethnicity & disease, 17(3)555-9 Abstract

  • Saracino MR, Lampe JW (2007) Phytochemical regulation of UDP-glucuronosyltransferases: implications for cancer prevention., Nutrition and cancer, 59(2)121-41 Abstract

  • Newton, K.M., Lacroix, A.Z., Levy, L., Li, S.S., Qu, P., Potter, J.K., Lampe, J.W. (2006) Soy protein and bone mineral density in older men and women: A randomized trial, Maturitas, 55, 270-7, Published

  • Messina, M (2006) An overview of the health effects of isoflavones with an emphasis on prostate cancer risk and prostate-specific antigen levels, J AOAC, 89, 1121-1134, Published

  • Velicer, C.M., Heckbert, S.R., Rutter, C., Lampe, J.W., Malone, K. (2006) Association between antibiotic use prior to breast cancer diagnosis and breast tumour characteristics, Cancer Causes & Control, 17(3)307-13, Published

  • Thomas, S.S., Li, S.S., Lampe, J.W., Potter, J.D., Bigler, J. (2006) Genetic variability, haplotypes, and htSNPs for exons 1 at the human UGT1A locus, Human Mutation, 27(7)717, Published

  • McVeigh, B.L., Dillingham, B.L., Lampe, J.W., Duncan, A.M. (2006) Effect of soy protein varying in isoflavone content on serum lipids in healthy young men, American Journal of Clinical Nutrition, 83(2)244-51, Published

  • Kuehl, G.E., Bigler, J., Potter, J.D., Lampe, J.W. (2006) Glucuronidation of the aspirin metabolite salicylic acid by expressed UDP-glucuronosyltransferases and human liver microsomes, Drug Metabolism and Disposition, 34(2)199-202, Published

  • Frankenfeld, C.L., McTiernan, A., Thomas, W.K., LaCroix, K., McVarish, L., Holt, V.L., Schwartz, S.M., Lampe, J.W. (2006) Postmenopausal bone mineral density in relation to soy isoflavone-metabolizing phenotypes, Maturitas, 53(3)315-24, Published

  • Song, K.B., Atkinson, C., Frankenfeld, C.L., Jokela, T., Wähälä, K., Thomas, W.K., Lampe, J.W. (2006) Prevalence of daidzein-metabolizing phenotypes differs between Caucasian and Korean American women and girls, The Journal of Nutrition, 136(5)1247-51, Published

  • Chang, J.L., Chen, G., Lampe, J.W., Ulrich, C.M. (2006) DNA damage and repair measurements from cryopreserved lymphocytes without cell culture-A reproducible assay for intervention studies, Environmental and Molecular Mutagenesis, 47, 503-508, Published

  • Peterson, S., Lampe, J.W., Bammler, T.K., Gross-Steinmeyer, K., Eaton, D.L. (2006) Apiaceous vegetable constituents inhibit human cytochrome P-450 1A2 (hCYP1A2) activity and hCYP1A2-mediated mutagenicity of aflatoxin B(1), Food and Chemical Toxicology, 44(9)1474-84, Published

  • Adams KF, Lampe PD, Newton KM, Ylvisaker JT, Feld A, Myerson D, Emerson SS, White E, Potter JD, Lampe JW (Sep 2005) Soy protein containing isoflavones does not decrease colorectal epithelial cell proliferation in a randomized controlled trial, The American Journal of Clinical Nutrition, 82(3)620-6 Abstract

  • Li SS, Bigler J, Lampe JW, Potter JD, Feng Z (Aug 2005) FDR-controlling testing procedures and sample size determination for microarrays, Statistics in Medicine, 24(15)2267-80 Abstract

  • Kuehl GE, Lampe JW, Potter JD, Bigler J (Jul 2005) Glucuronidation of nonsteroidal anti-inflammatory drugs: identifying the enzymes responsible in human liver microsomes, Drug Metabolism and Disposition: the Biological Fate of Chemicals, 33(7)1027-35 Abstract

  • Li W, Ray RM, Lampe JW, Lin MG, Gao DL, Wu C, Nelson ZC, Fitzgibbons ED, Horner N, Hu YW, Shannon J, Satia JA, Patterson RE, Stalsberg H, Thomas DB (Jul 2005) Dietary and other risk factors in women having fibrocystic breast conditions with and without concurrent breast cancer: a nested case-control study in Shanghai, China, International Journal of Cancer. Journal International Du Cancer, 115(6)981-93 Abstract

  • Peterson S, Bigler J, Horner NK, Potter JD, Lampe JW, Cruciferae Interact With the UGT1A1*28 Polymorphism to Determine Serum Bilirubin Levels in Humans., The Journal of Nutrition, 135(5):1051-5, May 2005 Abstract

  • West SG, Hilpert KF, Juturu V, Bordi PL, Lampe JW, Mousa SA, Kris-Etherton PM (Apr 2005) Effects of including soy protein in a blood cholesterol-lowering diet on markers of cardiac risk in men and in postmenopausal women with and without hormone replacement therapy, Journal of Women's Health (2002), 14(3)253-62 Abstract

  • Atkinson C, Frankenfeld CL, Lampe JW, Gut Bacterial Metabolism of the Soy Isoflavone Daidzein: Exploring The Relevance to Human Health., Experimental Biology and Medicine (maywood, N.j.), 230(3):155-70, Mar 2005 Abstract

  • Dillingham BL, McVeigh BL, Lampe JW, Duncan AM, Soy Protein Isolates of Varying Isoflavone Content Exert Minor Effects On Serum Reproductive Hormones in Healthy Young Men., The Journal of Nutrition, 135(3):584-91, Mar 2005 Abstract

  • Rudolph RE, Dominitz JA, Lampe JW, Levy L, Qu P, Li SS, Lampe PD, Bronner MP, Potter JD (Mar 2005) Risk factors for colorectal cancer in relation to number and size of aberrant crypt foci in humans, Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 14(3)605-8 Abstract

  • Kreijkamp-Kaspers S, Kok L, Bots ML, Grobbee DE, Lampe JW, van der Schouw YT, Randomized Controlled Trial of the Effects of Soy Protein Containing Isoflavones on Vascular Function in Postmenopausal Women., The American Journal of Clinical Nutrition, 81(1):189-95, Jan 2005 Abstract

  • Shannon J, Ray R, Wu C, Nelson Z, Gao DL, Li W, Hu W, Lampe J, Horner N, Satia J, Patterson R, Fitzgibbons D, Porter P, Thomas D, Food and Botanical Groupings and Risk of Breast Cancer: a Case-control Study in Shanghai, China., Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored By the American Society of Preventive Oncology., 14(1):81-90, Jan 2005 Abstract

  • Frankenfeld, C.L., Atkinson, C., Thomas, W.K., Gonzalez, A., Jokela, T., Wähälä, K., Schwartz, S.M., Li, S.S., Lampe, J.W. (2005) High concordance of daidzein-metabolizing phenotypes in individuals measured one to three years apart, The British Journal of Nutrition, 94, 873-876, Published

  • Kok, L., Kreijkamp-Kaspers, S., Grobbee, D.E., Lampe, J.W., van der Schouw, Y.T. (2005) Soy isoflavones, body composition, and physical performance, Maturitas, 94, 873-876, Published

  • Kok L, Kreijkamp-Kaspers S, Grobbee DE, Lampe JW, van der Schouw YT, A Randomized, Placebo-controlled Trial on the Effects of Soy Protein Containing Isoflavones on Quality of Life in Postmenopausal Women., Menopause (new York, N.y.), 12(1):56-62, Jan-Feb 2005 Abstract

  • Kok L, Kreijkamp-Kaspers S, Grobbee DE, Lampe JW, van der Schouw YT (Jan-Feb 2005) A randomized, placebo-controlled trial on the effects of soy protein containing isoflavones on quality of life in postmenopausal women, Menopause (new York, N.y.), 12(1)56-62 Abstract

  • Lampe JW, Nutrition and Cancer Prevention: Small-scale Human Studies for the 21st Century., Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored By the American Society of Preventive Oncology., 13(12):1987-8, Dec 2004 Abstract

  • Wu C, Ray RM, Lin MG, Gao DL, Horner NK, Nelson ZC, Lampe JW, Hu YW, Shannon J, Stalsberg H, Li W, Fitzgibbons D, Porter P, Patterson RE, Satia JA, Thomas DB, A Case-control Study of Risk Factors for Fibrocystic Breast Conditions: Shanghai Nutrition and Breast Disease Study, China, 1995-2000., American Journal of Epidemiology, 160(10):945-60, Nov 2004 Abstract

  • Frankenfeld CL, Atkinson C, Thomas WK, Goode EL, Gonzalez A, Jokela T, Wahala K, Schwartz SM, Li SS, Lampe JW (Oct 2004) Familial correlations, segregation analysis, and nongenetic correlates of soy isoflavone-metabolizing phenotypes, Experimental Biology and Medicine (maywood, N.j.), 229(9)902-13 Abstract

  • Prentice RL, Willett WC, Greenwald P, Alberts D, Bernstein L, Boyd NF, Byers T, Clinton SK, Fraser G, Freedman L, Hunter D, Kipnis V, Kolonel LN, Kristal BS, Kristal A, Lampe JW, McTiernan A, Milner J, Patterson RE, Potter JD, Riboli E, Schatzkin A, Yates A, Yetley E, Nutrition and Physical Activity and Chronic Disease Prevention: Research Strategies and Recommendations., Journal of the National Cancer Institute, 96(17):1276-87, Sep 2004 Abstract

  • Frankenfeld CL, Lampe JW, Shannon J, Gao DL, Ray RM, Prunty J, Kalhorn TF, Wahala K, Patterson RE, Thomas DB (Sep 2004) Frequency of soy food consumption and serum isoflavone concentrations among Chinese women in Shanghai, Public Health Nutrition, 7(6)765-72 Abstract

  • Kreijkamp-Kaspers S, Kok L, Grobbee DE, de Haan EH, Aleman A, Lampe JW, van der Schouw YT, Effect of soy protein containing isoflavones on cognitive function, bone mineral density, and plasma lipids in postmenopausal women: a randomized controlled trial, Jama : the Journal of the American Medical Association, 292(1):65-74, July 2004 Abstract

  • Frankenfeld CL, McTiernan A, Aiello EJ, Thomas WK, LaCroix K, Schramm J, Schwartz SM, Holt VL, Lampe JW (Jul 2004) Mammographic density in relation to daidzein-metabolizing phenotypes in overweight, postmenopausal women, Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 13(7)1156-62 Abstract

  • Radich JP, Mao M, Stepaniants S, Biery M, Castle J, Ward T, Schimmack G, Kobayashi S, Carleton M, Lampe J, Linsley PS (Jun 2004) Individual-specific variation of gene expression in peripheral blood leukocytes, Genomics, 83(6)980-8 Abstract

  • Erdman JW Jr, Badger TM, Lampe JW, Setchell KD, Messina M, Not all soy products are created equal: caution needed in interpretation of research results, The Journal of Nutrition, 134(5):1229S-1233S, May 2004 Abstract

  • Atkinson C, Lampe JW, Tworoger SS, Ulrich CM, Bowen D, Irwin ML, Schwartz RS, Rajan BK, Yasui Y, Potter JD, McTiernan A, Effects of a moderate intensity exercise intervention on estrogen metabolism in postmenopausal women, Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology., 13(5):868-74, May 2004 Abstract

  • Frankenfeld CL, McTiernan A, Tworoger SS, Atkinson C, Thomas WK, Stanczyk FZ, Marcovina SM, Weigle DS, Weiss NS, Holt VL, Schwartz SM, Lampe JW, Serum steroid hormones, sex hormone-binding globulin concentrations, and urinary hydroxylated estrogen metabolites in post-menopausal women in relation to daidzein-metabolizing phenotypes, The Journal of Steroid Biochemistry and Molecular Biology, 88(4-5):399-408, April 2004 Abstract

  • Adams KF, Chen C, Newton KM, Potter JD, Lampe JW, Soy Isoflavones Do Not Modulate Prostate-specific Antigen Concentrations in Older Men in a Randomized Controlled Trial., Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored By the American Society of Preventive Oncology., 13(4):644-8, Apr 2004 Abstract

  • Newcomb PA, Bush AC, Stoner GL, Lampe JW, Potter JD, Bigler J, No Evidence of An Association of JC Virus and Colon Neoplasia., Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored By the American Society of Preventive Oncology., 13(4):662-6, Apr 2004 Abstract

  • Atkinson C, Berman S, Humbert O, Lampe JW, In vitro incubation of human feces with daidzein and antibiotics suggests interindividual differences in the bacteria responsible for equol production, The Journal of Nutrition, 134(3):596-9, March 2004 Abstract

  • Lampe JW, Stepaniants SB, Mao M, Radich JP, Dai H, Linsley PS, Friend SH, Potter JD, Signatures of environmental exposures using peripheral leukocyte gene expression: tobacco smoke, Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology., 13(3):445-53, March 2004 Abstract

  • Velicer CM, Heckbert SR, Lampe JW, Potter JD, Robertson CA, Taplin SH, Antibiotic use in relation to the risk of breast cancer, Jama : the Journal of the American Medical Association, 291(7):827-35, February 2004 Abstract

  • Tworoger SS, Chubak J, Aiello EJ, Ulrich CM, Atkinson C, Potter JD, Yasui Y, Stapleton PL, Lampe JW, Farin FM, Stanczyk FZ, McTiernan A, Association of CYP17, CYP19, CYP1B1, and COMT polymorphisms with serum and urinary sex hormone concentrations in postmenopausal women, Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology., 13(1):94-101, January 2004 Abstract

  • Velicer CM, Lampe JW, Heckbert SR, Potter JD, Taplin SH (Oct 2003) Hypothesis: is antibiotic use associated with breast cancer?, Cancer Causes & Control : Ccc, 14(8)739-47 Abstract

  • Neuhouser ML, Patterson RE, King IB, Horner NK, Lampe JW (Oct 2003) Selected nutritional biomarkers predict diet quality, Public Health Nutrition, 6(7)703-9 Abstract

  • Lampe JW, Spicing up a vegetarian diet: chemopreventive effects of phytochemicals, The American Journal of Clinical Nutrition, 78(3 Suppl):579S-583S, September 2003 Abstract

  • Atkinson C, Skor HE, Dawn Fitzgibbons E, Scholes D, Chen C, Wahala K, Schwartz SM, Lampe JW, Urinary equol excretion in relation to 2-hydroxyestrone and 16alpha-hydroxyestrone concentrations: an observational study of young to middle-aged women, Journal of Steroid Biochemistry and Molecular Biology, 86(1):71-7, July 2003 Abstract

  • Adams KF, Newton KM, Chen C, Emerson SS, Potter JD, White E, Lampe JW, Soy isoflavones do not modulate circulating insulin-like growth factor concentrations in an older population in an intervention trial, Journal of Nutrition, 133(5):1316-9, May 2003 Abstract

  • Lampe JW, Isoflavonoid and lignan phytoestrogens as dietary biomarkers, Journal of Nutrition, 133 Suppl 3, 956S-964S, March 2003 Abstract

  • Frankenfeld CL, Patterson RE, Horner NK, Neuhouser ML, Skor HE, Kalhorn TF, Howald WN, Lampe JW, Validation of a soy food-frequency questionnaire and evaluation of correlates of plasma isoflavone concentrations in postmenopausal women, The American Journal of Clinical Nutrition, 77(3):674-80, March 2003 Abstract

  • Neuhouser ML, Patterson RE, King IB, Horner NK, Lampe JW, Selected nutritional biomarkers predict diet quality, Public Health Nutrition, 6, 703-709, 2003

  • Adams, K.F., Newton, K.M., Chen, C., Emerson, S.S., Potter, J.D., Lampe, J.W. (2003) Soy isoflavones do not modulate insulin-like growth factors in an older population: a randomized controlled trial, The Journal of Nutrition, 1316-1319, Published

  • Lampe JW, Peterson S, Brassica, biotransformation and cancer risk: genetic polymorphisms alter the preventive effects of cruciferous vegetables, Journal of Nutrition, 132(10):2991-4, October 2002

  • Frankenfeld CL, Patterson RE, Kalhorn TF, Skor HE, Howald WN, Lampe JW (Oct 2002) Validation of a soy food frequency questionnaire with plasma concentrations of isoflavones in US adults, Journal of the American Dietetic Association, 102(10)1407-13 Abstract

  • Horner NK, Patterson RE, Neuhouser ML, Lampe JW, Beresford SA, Prentice RL (Oct 2002) Participant characteristics associated with errors in self-reported energy intake from the Women's Health Initiative food-frequency questionnaire, The American Journal of Clinical Nutrition, 76(4)766-73 Abstract

  • Lampe JW, Li SS, Potter JD, King IB, Serum beta-glucuronidase activity is inversely associated with plant-food intakes in humans, Journal of Nutrition, 132(6):1341-4, June 2002

  • Atkinson C, Skor HE, Fitzgibbons ED, Scholes D, Chen C, Wahala K, Schwartz SM, Lampe JW (Mar 2002) Overnight urinary isoflavone excretion in a population of women living in the United States, and its relationship to isoflavone intake, Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 11(3)253-60 Abstract

  • Kristal AR, Lampe JW (2002) Brassica vegetables and prostate cancer risk: a review of the epidemiological evidence, Nutrition and Cancer, 42(1)1-9 Abstract

  • Horner NK, Kristal AR, Prunty J, Skor HE, Potter JD, Lampe JW (Jan 2002) Dietary determinants of plasma enterolactone, Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 11(1)121-6 Abstract

  • Messina M, Lampe JW, Birt DF, Appel LJ, Pivonka E, Berry B, Jacobs DR Jr (Dec 2001) Reductionism and the narrowing nutrition perspective: time for reevaluation and emphasis on food synergy, Journal of the American Dietetic Association, 101(12)1416-9 Abstract

  • Rice MM, LaCroix AZ, Lampe JW, van Belle G, Kestin M, Sumitani M, Graves AB, Larson EB (Oct 2001) Dietary soy isoflavone intake in older Japanese American women, Public Health Nutrition, 4(5)943-52 Abstract

  • Horner NK, Lampe JW, Patterson RE, Neuhouser ML, Beresford SA, Prentice RL, Indirect calorimetry protocol development for measuring resting metabolic rate as a component of total energy expenditure in free-living postmenopausal women, Journal of Nutrition, 131(8):2215-8, August 2001 Abstract

  • Bigler J, Whitton J, Lampe JW, Fosdick L, Bostick RM, Potter JD, CYP2C9 and UGT1A6 genotypes modulate the protective effect of aspirin on colon adenoma risk, Cancer Research, 61(9):3566-9, 2001 Abstract

  • Lampe JW, Skor HE, Li S, Wahala K, Howald WN, Chen C, Wheat bran and soy protein feeding do not alter urinary excretion of the isoflavan equol in premenopausal women, Journal of Nutrition, 131(3):740-4, March 2001 Abstract

  • Horner NK, Lampe JW, Potential mechanisms of diet therapy for fibrocystic breast conditions show inadequate evidence of effectiveness, Journal of the American Dietetic Association, 100(11):1368-80, November 2000 Abstract

  • Lampe JW, Chen C, Li S, Prunty J, Grate MT, Meehan DE, Barale KV, Dightman DA, Feng Z, Potter JD (Aug 2000) Modulation of human glutathione S-transferases by botanically defined vegetable diets, Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 9(8)787-93 Abstract

  • Lampe JW, King IB, Li S, Grate MT, Barale KV, Chen C, Feng Z, Potter JD, Brassica vegetables increase and apiaceous vegetables decrease cytochrome P450 1A2 activity in humans: changes in caffeine metabolite ratios in response to controlled vegetable diets, Carcinogenesis, 21(6):1157-62, June 2000 Abstract

  • Lampe JW, Bigler J, Bush AC, Potter JD, Prevalence of polymorphisms in the human UDP-glucuronosyltransferase 2B family: UGT2B4(D458E), UGT2B7(H268Y), and UGT2B15(D85Y), Cancer Epidemiology, Biomarkers and Prevention, 9(3):329-33, March 2000 Abstract

  • Rock CL, Lampe JW, Patterson RE (2000) Nutrition, genetics, and risks of cancer, Annual Review of Public Health, 21, 47-64 Abstract

  • Lampe JW, Health effects of vegetables and fruit: assessing mechanisms of action in human experimental studies., American Journal of Clinical Nutrition, 70(3 Suppl):475S-490S, September 1999 Abstract

  • Lampe JW, Gustafson DR, Hutchins AM, Martini MC, Li S, Wahala K, Grandits GA, Potter JD, Slavin JL, Urinary isoflavonoid and lignan excretion on a Western diet: relation to soy, vegetable, and fruit intake, Cancer Epidemiology, Biomarkers and Prevention, 8(8):699-707, August 1999 Abstract

  • Lampe JW, Bigler J, Horner NK, Potter JD, UDP-glucuronosyltransferase (UGT1A1*28 and UGT1A6*2) polymorphisms in Caucasians and Asians: relationships to serum bilirubin concentrations, Pharmacogenetics, 9(3):341-9, June 1999 Abstract

  • Kirk P, Patterson RE, Lampe J (May 1999) Development of a soy food frequency questionnaire to estimate isoflavone consumption in US adults, Journal of the American Dietetic Association, 99(5)558-63 Abstract

  • Slavin JL, Karr SC, Hutchins AM, Lampe JW, Influence of soybean processing, habitual diet, and soy dose on urinary isoflavonoid excretion, American Journal of Clinical Nutrition, 68(6 Suppl):1492S-1495S, December 1998 Abstract

  • Lampe JW, Karr SC, Hutchins AM, Slavin JL, Urinary equol excretion with a soy challenge: influence of habitual diet, Proceedings of the Society for Experimental Biology and Medicine, 217(3):335-9, March 1998 Abstract

  • Lampe JW, Karr SC, Hutchins AM, Slavin JL (Mar 1998) Urinary equol excretion with a soy challenge: influence of habitual diet, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (new York, N. Y.), 217(3)335-9 Abstract

  • Karr SC, Lampe JW, Hutchins AM, Slavin JL, Urinary isoflavonoid excretion in humans is dose dependent at low to moderate levels of soy-protein consumption, American Journal of Clinical Nutrition, 66(1):46-51, July 1997 Abstract

  • Sivam GP, Lampe JW, Ulness B, Swanzy SR, Potter JD, Helicobacter pylori--in vitro susceptibility to garlic (Allium sativum) extract, Nutrition and Cancer, 27(2):118-21, 1997 Abstract

  • Hutchins AM, Lampe JW, Martini MC, Campbell DR, Slavin JL, Vegetables, fruits, and legumes: effect on urinary isoflavonoid phytoestrogen and lignan excretion, Journal of the American Dietetic Association, 95(7):769-74, July 1995 Abstract

  • Kurzer MS, Lampe JW, Martini MC, Adlercreutz H, Fecal lignan and isoflavonoid excretion in premenopausal women consuming flaxseed powder, Cancer Epidemiology, Biomarkers and Prevention, 4(4):353-8, June 1995 Abstract

  • Hutchins AM, Slavin JL, Lampe JW, Urinary isoflavonoid phytoestrogen and lignan excretion after consumption of fermented and unfermented soy products, Journal of the American Dietetic Association, 95(5):545-51, May 1995 Abstract

  • Kirkman LM, Lampe JW, Campbell DR, Martini MC, Slavin JL, Urinary lignan and isoflavonoid excretion in men and women consuming vegetable and soy diets, Nutrition and Cancer, 24(1):1-12, 1995 Abstract

  • Martini MC, Lampe JW, Slavin JL, Kurzer MS, Effect of the menstrual cycle on energy and nutrient intake, American Journal of Clinical Nutrition, 60(6):895-9, December 1994 Abstract

  • Lampe JW, Martini MC, Kurzer MS, Adlercreutz H, Slavin JL, Urinary lignan and isoflavonoid excretion in premenopausal women consuming flaxseed powder, American Journal of Clinical Nutrition, 60(1):122-8, July 1994 Abstract

  • Fredstrom SB, Lampe JW, Jung HJ, Slavin JL, Apparent fiber digestibility and fecal short-chain fatty acid concentrations with ingestion of two types of dietary fiber [published erratum appears in JPEN J Parenter Enteral Nutr 1994 Mar-Apr;18(2):, Jpen. Journal of Parenteral and Enteral Nutrition, 18(1):14-9, 1994 Abstract

  • Adlercreutz H, Fotsis T, Watanabe S, Lampe J, Wahala K, Makela T, Hase T (1994) Determination of lignans and isoflavonoids in plasma by isotope dilution gas chromatography-mass spectrometry, Cancer Detection and Prevention, 18(4)259-71 Abstract

  • Phipps WR, Martini MC, Lampe JW, Slavin JL, Kurzer MS, Effect of flax seed ingestion on the menstrual cycle, Journal of Clinical Endocrinology and Metabolism, 77(5):1215-9, November 1993 Abstract

  • Lampe JW, Wetsch RF, Thompson WO, Slavin JL, Gastrointestinal effects of sugarbeet fiber and wheat bran in healthy men, European Journal of Clinical Nutrition, 47(8):543-8, August 1993 Abstract

  • Lampe JW, Fredstrom SB, Slavin JL, Potter JD, Sex differences in colonic function: a randomised trial, Gut, 34(4):531-6, April 1993 Abstract

  • Bostick RM, Potter JD, Fosdick L, Grambsch P, Lampe JW, Wood JR, Louis TA, Ganz R, Grandits G, Calcium and colorectal epithelial cell proliferation: a preliminary randomized, double-blinded, placebo-controlled clinical trial, Journal of the National Cancer Institute, 85(2):132-41, January 1993 Abstract

  • Adlercreutz, H., Fotsis, T., Lampe, J., Wähälä, K., Mäkelä, T., Brunow, G., Hase, T. (1993) Studies on the quantitative determination of lignans and isoflavonoids in plasma by isotope dilution gas chromatography-mass spectrometry, Scandinavian Journal of Clinical and Laboratory Investigation, 53(suppl)5-18, Published

  • Lampe JW, Effertz ME, Larson JL, Slavin JL, Gastrointestinal effects of modified guar gum and soy polysaccharide as part of an enteral formula diet, Jpen. Journal of Parenteral and Enteral Nutrition, 16(6):538-44, 1992 Abstract

  • Schneider, C.M., Rogers, M.A., Lampe, J.W., Rhodes, M.C., Apple, F.S. (1992) Serum creatine kinase isoenzyme measurements in master male and female marathon runners, Sports Medical Training and Rehabilitation(3)237-242, Published

  • Slavin, J.L., Lampe, J.W. (1992) The health benefits of rice bran in human nutrition, Cereal Foods World(37)760-764, Published

  • Lampe JW, Slavin JL, Melcher EA, Potter JD (Mar-Apr 1992) Effects of cereal and vegetable fiber feeding on potential risk factors for colon cancer, Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 1(3)207-11 Abstract

  • Fredstrom SB, Baglien KS, Lampe JW, Slavin JL, Determination of the fiber content of enteral feedings, Jpen. Journal of Parenteral and Enteral Nutrition, 15(4):450-3, 1991 Abstract

  • Lampe JW, Slavin JL, Baglien KS, Thompson WO, Duane WC, Zavoral JH, Serum lipid and fecal bile acid changes with cereal, vegetable, and sugar-beet fiber feeding, American Journal of Clinical Nutrition, 53(5):1235-41, May 1991 Abstract

  • Lampe JW, Slavin JL, Apple FS, Iron status of active women and the effect of running a marathon on bowel function and gastrointestinal blood loss, International Journal of Sports Medicine, 12(2):173-9, April 1991 Abstract

  • Lampe, J.W., Slavin, J.L., Baglien, K.S., Thompson, W.O., Duane, W.C., Zavoral, J.H. (1991) Effects of cereal, vegetable, and sugar beet fiber feeding on serum lipids and fecal bile acid excretion, The American Journal of Clinical Nutrition(53)1235-1241, Published

  • Apple FS, Rogers MA, Casal DC, Lewis L, Ivy JL, Lampe JW (1987) Skeletal muscle creatine kinase MB alterations in women marathon runners, European Journal of Applied Physiology and Occupational Physiology, 56(1)49-52 Abstract

  • Lampe JW, Slavin JL, Apple FS (Apr 1986) Poor iron status of women runners training for a marathon, International Journal of Sports Medicine, 7(2)111-4 Abstract

  • Lampe, J.W., Slavin, J.L., Apple, F.S. (1986) Effects of moderate iron supplementation on the iron status of runners with low serum ferritin concentrations, Nutrition Reports International(34)959-965, Published

  • Lampe JW, Slavin JL, Apple FS (1986) Elevated serum ferritin concentrations in master runners after a marathon race, International Journal for Vitamin and Nutrition Research. Internationale Zeitschrift Fur Vitamin- Und Ernahrungsforschung. Journal International De Vitaminologie Et De Nutrition, 56(4)395-8 Abstract
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Last Updated: Mar 24 2009.

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Individual Expertise profile of Johanna W. Lampe, Copyright Johanna W. Lampe.
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